Laboratory Information Management Software for genotyping workflows: applications in high throughput crop genotyping
نویسندگان
چکیده
منابع مشابه
High-Throughput SNP Genotyping to Accelerate Crop Improvement
Recent advances in next-generation sequencing (NGS) and single nucleotide polymorphism (SNP) genotyping promise to greatly accelerate crop improvement if properly deployed. High-throughput SNP genotyping offers a number of advantages over previous marker systems, including an abundance of markers, rapid processing of large populations, a variety of genotyping systems to meet different needs, an...
متن کاملHigh-Throughput SNP Genotyping
Whole genome approaches using single nucleotide polymorphism (SNP) markers have the potential to transform complex disease genetics and expedite pharmacogenetics research. This has led to a requirement for high-throughput SNP genotyping platforms. Development of a successful high-throughput genotyping platform depends on coupling reliable assay chemistry with an appropriate detection system to ...
متن کاملHigh-throughput genotyping with single nucleotide polymorphisms.
To make large-scale association studies a reality, automated high-throughput methods for genotyping with single-nucleotide polymorphisms (SNPs) are needed. We describe PCR conditions that permit the use of the TaqMan or 5' nuclease allelic discrimination assay for typing large numbers of individuals with any SNP and computational methods that allow genotypes to be assigned automatically. To dem...
متن کاملWTSI High-throughput Genotyping Quality Assessment & Control
Description The Genotyping Facility at the Wellcome Trust Sanger Institute (WTSI) is operated by Team 67 – Genetics of complex traits in humans, led by Panos Deloukas. While the quality control (QC) pipeline extends from sample reception (DNA collections team) to the secure end-point dissemination of the genotype data, herein we concentrate primarily on the bioinformatic characterization and fi...
متن کاملKwok, "High-Throughput Genotyping Assay Approaches"
High-throughput genotyping approaches are being developed to meet the demands of pharmacogenomics, where numerous individuals are studied with thousands of single nucleotide polymorphism (SNP) markers. All non-gel-based genotyping approaches achieve allelic discrimination by one of four mechanisms: allele-specific hybridisation, allele-specific primer extension, allele-specific oligonucleotide ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2006
ISSN: 1471-2105
DOI: 10.1186/1471-2105-7-383